UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, DC 20549

 

SCHEDULE 13D

 

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 2)*

 

NuCana plc

 

(Name of Issuer)

 

Ordinary Shares

 

(Title of Class of Securities)

 

67022C106

 

(CUSIP Number)

 

Armance Bordes

Sofinnova Partners SAS

7-11 blvd Haussmann

75009 Paris

France

+33 1 76 23 41 09

 

(Name, Address and Telephone Number of Person

Authorized to Receive Notices and Communications)

 

December 31, 2019

 

(Date of Event Which Requires Filing of this Statement)

 

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ¨

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

 

 

 

 

CUSIP No. 67022C106 Page 2 of 10

 

1.   

Name of Reporting Persons

 

Sofinnova Capital VI FCPR (“SC VI”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                

x               

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

WC

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨               
6.

Citizenship or Place of Organization

 

France

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares), except that Sofinnova Partners SAS, a French corporation (“SP SAS”), the management company of SC VI, may be deemed to have sole voting power, and Denis Lucquin (“Lucquin”), Antoine Papiernik (“Papiernik”), Henrijette Richter (“Richter”), Monique Saulnier (“Saulnier”) and Graziano Seghezzi (“Seghezzi”), the managing partners of SP SAS, may be deemed to have shared power to vote these shares.

8.

Shared Voting Power

 

See row 7.

9.

Sole Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares), except that SP SAS, the management company of SC VI, may be deemed to have sole power to dispose of these shares, and Lucquin, Papiernik, Richter, Saulnier and Seghezzi, the managing partners of SP SAS, may be deemed to have shared power to dispose of these shares.

10.

Shared Dispositive Power

 

See row 9.

 

11.          

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

12.           Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions) ¨                                                                                                 
13.          

Percent of Class Represented by Amount in Row 11

 

21.2%

14.          

Type of Reporting Person (see instructions)

 

00

 

 

 

 

CUSIP No. 67022C106 Page 3 of 10

 

1.

Name of Reporting Persons

 

Sofinnova Partners SAS, a French corporation (“SP SAS”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                    

x                   

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                   
6.

Citizenship or Place of Organization

 

France

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares). SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Lucquin, Papiernik, Richter, Saulnier and Seghezzi, the managing partners of SP SAS, may be deemed to have shared power to vote these shares.

8.

Shared Voting Power

 

See row 7.

9.

Sole Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares), except that SP SAS, the management company of SC VI, may be deemed to have sole power to dispose of these shares, and Lucquin, Papiernik, Richter, Saulnier and Seghezzi, the managing partners of SP SAS, may be deemed to have shared power to dispose of these shares.

10.

Shared Dispositive Power

 

See row 9.

11.          

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

12.           Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions) ¨                                                                                                   
13.          

Percent of Class Represented by Amount in Row 11

 

21.2%

14.          

Type of Reporting Person (see instructions)

 

00

 

 

 

 

 

CUSIP No. 04351P101 Page 4 of 10

 

1.

Name of Reporting Persons

 

Denis Lucquin (“Lucquin”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                                                                                 

x                                                                                

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                                                                                 
6.

Citizenship or Place of Organization

 

French Citizen

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

0

8.

Shared Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares). SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Lucquin, a managing partner of SP SAS, may be deemed to have shared power to vote these shares.

9.

Sole Dispositive Power

 

0

10.

Shared Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by American depositary shares). SP SAS, the management company of SC VI, may be deemed to have power to dispose of these shares, and Lucquin, a managing partner of SP SAS, may be deemed to have shared power to dispose of these shares.

 

11.          

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

 

12.          

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions)

 

¨                                                                                  
13.          

Percent of Class Represented by Amount in Row 11

 

21.2%

 

14.          

Type of Reporting Person (see instructions)

 

IN

 

 

 

 

CUSIP No. 04351P101 Page 5 of 10

 

1.

Name of Reporting Persons

 

Antoine Papiernik (“Papiernik”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                                                                           

x                                                                          

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                                                                           
6.

Citizenship or Place of Organization

 

French Citizen

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

0

8.

Shared Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Papiernik, a managing partner of SP SAS, may be deemed to have shared power to vote these shares.

9.

Sole Dispositive Power

 

0

10.

Shared Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have power to dispose of these shares, and Papiernik, a managing partner of SP SAS, may be deemed to have shared power to dispose of these shares.

 

11.          

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

 

12.          

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions)

 

¨                                                                             
13.          

Percent of Class Represented by Amount in Row 11

 

21.2%

 

14.          

Type of Reporting Person (see instructions)

 

IN

 

 

 

 

CUSIP No. 04351P101 Page 6 of 10

 

1.

Name of Reporting Persons

 

Henrijette Richter (“Richter”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b) 

¨                                                              

x                                                             

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                                                              
6.

Citizenship or Place of Organization

 

Danish Citizen

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

0

8.

Shared Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Richter, a managing partner of SP SAS, may be deemed to have shared power to vote these shares.

9.

Sole Dispositive Power

 

0

10.

Shared Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have power to dispose of these shares, and Richter, a managing partner of SP SAS, may be deemed to have shared power to dispose of these shares.

 

11.          

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

12.          

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions)

 

¨                                                                 
13.          

Percent of Class Represented by Amount in Row 11

 

21.2%

 

14.          

Type of Reporting Person (see instructions)

 

IN

 

 

 

 

 

CUSIP No. 04351P101 Page 7 of 10

 

1.

Name of Reporting Persons

 

Monique Saulnier (“Saulnier”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                                                                          

x                                                                         

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                                                                          
6.

Citizenship or Place of Organization

 

French Citizen

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

0

8.

Shared Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Saulnier, a managing partner of SP SAS, may be deemed to have shared power to vote these shares.

9.

Sole Dispositive Power

 

0

10.

Shared Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have power to dispose of these shares, and Saulnier, a managing partner of SP SAS, may be deemed to have shared power to dispose of these shares.

 

11.            

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

12.              

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions)

 

¨                                                                        
13.

Percent of Class Represented by Amount in Row 11

 

21.2%

 

14.

Type of Reporting Person (see instructions)

 

IN

 

 

 

 

 

CUSIP No. 04351P101 Page 8 of 10

 

1.

Name of Reporting Persons

 

Graziano Seghezzi (“Seghezzi”)

2.

Check the Appropriate Box if a Member of a Group (see instructions)

(a)

(b)

¨                                                                              

x                                                                             

3.

SEC USE ONLY

 

4.

Source of Funds (see instructions)

 

00

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)

 

¨                                                                             
6.

Citizenship or Place of Organization

 

Italian Citizen

 

 

 

 

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

 

7.

Sole Voting Power

 

0

8.

Shared Voting Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have sole voting power, and Seghezzi, a managing partner of SP SAS, may be deemed to have shared power to vote these shares.

9.

Sole Dispositive Power

 

0

10.

Shared Dispositive Power

 

6,817,550 ordinary shares (including ordinary shares represented by ADSs), of which 6,817,550 shares are owned directly by SC VI. SP SAS, the management company of SC VI, may be deemed to have power to dispose of these shares, and Seghezzi, a managing partner of SP SAS, may be deemed to have shared power to dispose of these shares.

 

11.              

Aggregate Amount Beneficially Owned by Each Reporting Person

 

6,817,550

12.

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (see instructions)

 

¨                                                                            
13.

Percent of Class Represented by Amount in Row 11

 

21.2%

 

14.

Type of Reporting Person (see instructions)

 

IN

 

 

 

 

Page 9 of 10

 

Amendment No. 2 to Schedule 13D

 

This Amendment No. 2 (“Amendment No. 2”) amends and supplements the Schedule 13D filed with the Securities and Exchange Commission (the “SEC”) by Sofinnova Capital VI FCPR (“SC VI”), Sofinnova Partners SAS, a French corporation (“SP SAS”), Denis Lucquin (“Lucquin”), Antoine Papiernik (“Papiernik”), Henrijette Richter (“Richter”), Monique Saulnier (“Saulnier”), and Graziano Seghezzi (“Seghezzi”), the managing partners of SP SAS (collectively, the “Listed Persons” and together with SC VI and SP SAS, the “Reporting Persons”) on February 21, 2018, as amended by Amendment No. 1 to Schedule 13D filed with the SEC on February 14, 2019 (collectively, the “Schedule 13D”). Except as specifically provided herein, this Amendment No. 2 does not modify any of the information previously reported in the Schedule 13D, as amended. Capitalized terms used herein shall have the meanings ascribed to them in the Schedule 13D.

 

Item 2.Identity and Background

 

Item 2(b) of the Schedule 13D is hereby amended and restated as follows:

 

(b)The address of the principal place of business for each of the Reporting Persons is Sofinnova Partners SAS, 7-11 boulevard Hausmann 75009 Paris, France.

 

Item 2(c) of the Schedule 13D is hereby amended and restated as follows:

 

(c)The principal occupation of each of the Reporting Persons is the venture capital investment business. Each of the Listed Persons is employed at the offices of Sofinnova Partners SAS, 7-11 boulevard Hausmann 75009 Paris, France.

 

Item 5.Interest in Securities of the Issuer.

 

Item 5(c) of the Schedule 13D is hereby amended and supplemented as follows:

 

(c)SC VI sold ADSs of NuCana plc since the filing of the Schedule 13D on the following dates at the daily average prices indicated below:

 

Date  Shares   Per Share
Average Price
   How Effected 
April 8, 2019   5,358   $16.7636    Open Market 
April 9, 2019   1,910   $15.8207    Open Market 
April 10, 2019   1,900   $16.2935    Open Market 
April 11, 2019   101,200   $15.7579    Open Market 
April 12, 2019   92,500   $15.8015    Open Market 
April 15, 2019   13,377   $15.2829    Open Market 
April 16, 2019   10,410   $14.9676    Open Market 
April 17, 2019   1,400   $14.0321    Open Market 
April 18, 2019   1,001   $14.1906    Open Market 
April 22, 2019   900   $14.0661    Open Market 
April 26, 2019   186,289   $12.8000    Open Market 
Total:   416,245           

 

Item 7.Material to Be Filed as Exhibits.

 

Exhibit

   

Description

     
1.     Joint Filing Agreement, dated as of February 21, 2018, by and among Sofinnova Capital VI FCPR, Sofinnova Partners SAS, Denis Lucquin, Antoine Papiernik, Henrijette Richter, Monique Saulnier and Graziano Seghezzi (incorporated by reference to Exhibit A to the Schedule 13D filed by Sofinnova Capital VI FCPR on February 21, 2018).

 

 

 

 

Page 10 of 10

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

Dated: February 11, 2020

 

SOFINNOVA CAPITAL VI FCPR  
By: Sofinnova Partners SAS  
   
     
By: /s/ Monique Saulnier  
Name: Monique Saulnier  
Title: Managing Partner  
     
SOFINNOVA PARTNERS SAS  
   
     
By: /s/ Monique Saulnier  
Name: Monique Saulnier  
Title: Managing Partner  
     
By: /s/ Denis Lucquin  
Name: Denis Lucquin  
     
By: /s/ Antoine Papiernik  
Name:         Antoine Papiernik  
     
By: /s/ Henrijette Richter  
Name:        Henrijette Richter  
     
By: /s/ Monique Saulnier  
Name: Monique Saulnier  
     
By: /s/ Graziano Seghezzi  
Name: Graziano Seghezzi